#WEBDOT GRAPHVIZ SERIES#

6 The catalog data consist of the characteristic fragmentation patterns belonging to a set of specific substructures compiled from a library of known compounds present in the same sample that have also been characterized by other techniques.

applied a вЂњcatalog libraryвЂќ approach for elucidating the structures of minor components in a mixture of oligosaccharides. 5 Both GlycosidIQ and GlycoFragment/GlycoSearchMS utilize tandem MS (MS 2) of native samples and theoretically generated spectra as reference. Similarly, the GlycoFragment/GlycoSearchMS package compares each peak of an observed mass spectrum with the calculated fragments of all structures contained in the SweetDB database to support the interpretation of mass spectra of complex carbohydrates. GlycosidIQ 2 was developed for computerized interpretation of oligosaccharide spectra based on matching experimental data with theoretical fragments generated from GlycoSuiteDB, 3, 4 a database of glycan structures reported in the literature. The general reproducibility of ion trap (IT) spectra, and energy independence from the modes of ionization and collisional activation (CA), make compiling an MS n library an important research consideration.ДЄ number of oligosaccharide libraries have been reported each having specific characteristics applicable to the needs of independent research groups. In that regard, little could be more important than searchable spectral library files for structural confirmation. 1 With complete analysis as a practical consideration, there is a fundamental need for high-throughput tools to complement proteome studies.

#WEBDOT GRAPHVIZ SERIES#

The preceding report in this series presented data indicating that spectra from various stages of ion trap disassembly (MS n) could supply structural details for the characterization of linkage, monomer ID, and branching.

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